Cancer - What is deletion polymorphism glutathione-S-transferase mu

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Cancer - What is deletion polymorphism glutathione-S-transferase mu

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1. cancer deletion polymorphism glutathione-s-transferase mu

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• Thus, there was no significant increase in risk of incident breast cancer associated with the GSTM1 null genotype; however, the gene deletion polymorphism appeared to confer improved survival


• A common deletion polymorphism in the gene coding for the glutathione S-transferase class mu (the GSTM1 gene) results in a decreased ability to detoxify carcinogenic epoxide intermediates and has been associated with increased breast cancer risk in some small studies


• Glutathione S-transferase class mu deletion polymorphism and breast cancer: results from prevalent versus incident cases

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