What is cancer tositumomab?

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What is cancer tositumomab?

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1. cancer tositumomab

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• Rituximab 1997 CD20 Non-Hodgkin lymphoma Trastuzumab 1998 HER-2 Breast cancer Tositumomab 2003 CD20 Non-Hodgkin lymphoma Bevacizumab 2004 VEGF-A Colorectal cancer, breast cancer, non-squamous non small-cell lung cancer, renal cancer, glioma Cetuximab 2004 EGFR Colorectal cancer, head and neck squamous-cell carcinoma Panitumumab 2006 EGFR Colorectal cancer Ipilimumab 2011 CTLA-4 Melanoma


• The purpose of this study is to find the highest safe dose of Iodine-131 Tositumomab (Bexxar) that can be given to patients who have relapsed/refractory Hodgkin`s lymphoma, what side effects these patients get when they take Bexxar and if Bexxar is effective in treating relapsed/refractory Hodgkin`s lymphoma


• Duration of response of Hodgkin`s lymphoma to I-131 Tositumomab [TimeFrame:From time measurement criteria are met for response until first date that recurrent or progressive disease is objectively documented] [Designatedassafetyissue:No]

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