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Cancer - What is affected mutation carriers
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- cancer affected mutation carriers
Preview- It`s obvious that, the aim of the nowadays study was to calculate the cumulative hazard of LS related cancers in proven MLH1, MSH2 and MSH6 mutation carriers.
- It`s possible to notice, overall there were fifty four cancers recorded in three hundred sixty eight mutant carriers from one hundred seventy six families.
- It has been discovered that, the spectrum of cancers seen in a hospital based Lynch syndrome registry of mismatch repair gene (i.e., factor) mutation carriers was examined to determine the distribution of cancers and examine excess cancer risk. Syndrome is a set of symptoms or conditions that occur together and suggest the presence of a certain disease or an increased chance of developing the disease. Lynch syndrome is an inherited disorder in which affected individuals have a higher-than-normal chance of developing colorectal cancer and certain other types of cancer, often before the age of 50. Also called hereditary nonpolyposis colon cancer and HNPCC. Gene is the functional and physical unit of heredity passed from parent to offspring. Genes are pieces of DNA, and most genes contain the information for making a specific protein.
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