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What is cancer LMB-9 immunotoxin?
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- cancer lmb-9 immunotoxin
LMB-9 immunotoxin is a toxic substance linked to an antibody that attaches to tumor cells and kills them. Immunotoxin is an antibody linked to a toxic substance. Some immunotoxins can bind to cancer cells and kill them. Cancer is a term for diseases in which abnormal cells divide without control and can invade nearby tissues. Cancer cells can also spread to other parts of the body through the blood and lymph systems. There are several main types of cancer. Carcinoma is a cancer that begins in the skin or in tissues that line or cover internal organs. Sarcoma is a cancer that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Leukemia is a cancer that starts in blood-forming tissue such as the bone marrow, and causes large numbers of abnormal blood cells to be produced and enter the blood. Lymphoma and multiple myeloma are cancers that begin in the cells of the immune system. Central nervous system cancers are cancers that begin in the tissues of the brain and spinal cord. Also called malignancy.
Preview- You can recognize, to target the erb. B2 antigen expressed in poor-prognosis breast cancer and other carcinomas, several MAbs that vary in affinity have been cloned to produce recombinant single-chain or disulfide-stabilized immunotoxins. Prognosis is the likely outcome or course of a disease; the chance of recovery or recurrence. Breast, glandular organ located on the chest. The breast is made up of connective tissue, fat, and breast tissue that contains the glands that can make milk. Also called mammary gland. Breast cancer, cancer that forms in tissues of the breast, usually the ducts (tubes that carry milk to the nipple) and lobules (glands that make milk). It occurs in both men and women, although male breast cancer is rare. Antigen, any substance that causes the body to make a specific immune response. Recombinant is in genetics, describes DNA, proteins, cells, or organisms that are made by combining genetic material from two different sources. Recombinant substances are made in the laboratory and are being studied in the treatment of cancer and for many other uses. Affinity is in chemistry and biology, the strength of the attaction between two substances, such as two chemicals, or an antigen and an antibody.
- It`s possible to deduce that, in vitro and in vivo cytotoxic activities of recombinant immunotoxin 8. H9(Fv)-PE38 against breast cancer, osteosarcoma, and neuroblastoma. In vivo is in the body. The opposite of in vitro (outside the body or in the laboratory). Osteosarcoma is a cancer of the bone that usually affects the large bones of the arm or leg. It occurs most commonly in young people and affects more males than females. Also called osteogenic sarcoma. In vitro is in the laboratory (outside the body). The opposite of in vivo (in the body). Cytotoxic, cell-killing. Neuroblastoma, cancer that arises in immature nerve cells and affects mostly infants and children.
- You can notice, expression of HER2 in human gastric cancer cells directly correlates with antitumor activity of a recombinant disulfide-stabilized anti-HER2 immunotoxin. Antitumor, having to do with stopping abnormal cell growth. Gastric cancer, cancer that forms in tissues lining the stomach. Also called stomach cancer. Gastric, having to do with the stomach.
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