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What is cancer 6-hydroxymethylacylfulvene?
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- cancer 6-hydroxymethylacylfulvene
Cancer is a term for diseases in which abnormal cells divide without control and can invade nearby tissues. Cancer cells can also spread to other parts of the body through the blood and lymph systems. There are several main types of cancer. Carcinoma is a cancer that begins in the skin or in tissues that line or cover internal organs. Sarcoma is a cancer that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Leukemia is a cancer that starts in blood-forming tissue such as the bone marrow, and causes large numbers of abnormal blood cells to be produced and enter the blood. Lymphoma and multiple myeloma are cancers that begin in the cells of the immune system. Central nervous system cancers are cancers that begin in the tissues of the brain and spinal cord. Also called malignancy. 6-hydroxymethylacylfulvene is a substance being studied in the treatment of some types of cancer. 6-hydroxymethylacylfulvene attaches to the cell`s DNA and may block cancer cell growth. It is a type of alkylating agent. Also called irofulven.
Preview- It could seem to be apparant that, background The primary objective of this study was to assess the antitumor activity of irofulven in patients with hormone-refractory prostate cancer by measuring a sustained decrease of 50% or greater in serum prostate-specific antigen (PSA) levels. Hormone-refractory is in medicine, describes a disease or condition that does not respond to treatment with hormones. Also called hormone-resistant. PSA is a protein made by the prostate gland and found in the blood. PSA blood levels may be higher than normal in men who have prostate cancer, benign prostatic hyperplasia (BPH), or infection or inflammation of the prostate gland. Also called prostate-specific antigen. Serum is the clear liquid part of the blood that remains after blood cells and clotting proteins have been removed. Antitumor, having to do with stopping abnormal cell growth. Prostate-specific antigen is a protein made by the prostate gland and found in the blood. Prostate-specific antigen blood levels may be higher than normal in men who have prostate cancer, benign prostatic hyperplasia (BPH), or infection or inflammation of the prostate gland. Also called PSA. Prostate is a gland in the male reproductive system. The prostate surrounds the part of the urethra (the tube that empties the bladder) just below the bladder, and produces a fluid that forms part of the semen. Prostate cancer, cancer that forms in tissues of the prostate (a gland in the male reproductive system found below the bladder and in front of the rectum). Prostate cancer usually occurs in older men. Refractory is in medicine, describes a disease or condition that does not respond to treatment. Antigen, any substance that causes the body to make a specific immune response. Irofulven is a substance being studied in the treatment of some types of cancer. Irofulven attaches to the cell`s DNA and may block cancer cell growth. It is a type of alkylating agent. Also called 6-hydroxymethylacylfulvene. Hormone, one of many substances made by glands in the body. Hormones circulate in the bloodstream and control the actions of certain cells or organs. Some hormones can also be made in the laboratory.
- Apparently, chemotherapy, 6-hydroxymethylacylfulvene, irofulven, MGI 114, prostate cancer Chemotherapy, treatment with drugs that kill cancer cells.
- It would appear apparant that, conclusion Irofulven shows activity in hormone-refractory prostate cancer and has an acceptable safety profile, warranting further investigation of this drug, particularly in combination therapies.
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