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What is cancer AZT?
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- cancer azt
AZT is a drug that inhibits the human immunodeficiency virus (HIV) that causes AIDS. Also called zidovudine. Cancer is a term for diseases in which abnormal cells divide without control and can invade nearby tissues. Cancer cells can also spread to other parts of the body through the blood and lymph systems. There are several main types of cancer. Carcinoma is a cancer that begins in the skin or in tissues that line or cover internal organs. Sarcoma is a cancer that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Leukemia is a cancer that starts in blood-forming tissue such as the bone marrow, and causes large numbers of abnormal blood cells to be produced and enter the blood. Lymphoma and multiple myeloma are cancers that begin in the cells of the immune system. Central nervous system cancers are cancers that begin in the tissues of the brain and spinal cord. Also called malignancy.
Preview- One can recognize, falcone A, Lencioni M, Brunetti I, Pfanner E, Allegrini G, Antonuzzo A, Andreuccetti M, Malvaldi G, Danesi R, Del Tacca M, Conte PF 1997 Maximum tolerable doses of intravenous zidovudine in combination with 5-fluorouracil and leucovorin in metastatic colorectal cancer patients. Clinical evidence of significant antitumor activity and enhancement of zidovudine-induced DNA single strand breaks in peripheral nuclear blood cells. Antitumor, having to do with stopping abnormal cell growth. 5-fluorouracil is a drug used to treat cancers of the breast, stomach, and pancreas, and certain types of colorectal and head and neck cancers. It is also used in a cream to treat basal cell skin cancer and actinic keratosis (a skin condition that may become cancer). It is being studied in the treatment of other conditions and types of cancer. 5-fluorouracil stops cells from making DNA and it may kill cancer cells. It is a type of antimetabolite. Also called 5-FU, Adrucil, Efudex, Fluoroplex, and fluorouracil. Blood is a tissue with red blood cells, white blood cells, platelets, and other substances suspended in fluid called plasma. Blood takes oxygen and nutrients to the tissues, and carries away wastes. Colorectal, having to do with the colon or the rectum. Intravenous, into or within a vein. Intravenous usually refers to a way of giving a drug or other substance through a needle or tube inserted into a vein. Also called IV. Leucovorin is the active ingredient in a drug used to lessen the toxic effects of substances that block the action of folic acid, especially the anticancer drug methotrexate. Leucovorin is used to treat some types of anemia and is also used with fluorouracil to treat colorectal cancer. It is also being studied in the treatment of other types of cancer and other conditions. Leucovorin is a form of folic acid. It is a type of chemoprotective agent and a type of chemosensitizing agent. Also called folinic acid. Metastatic, having to do with metastasis, which is the spread of cancer from the primary site (place where it started) to other places in the body. Significant is in statistics, describes a mathematical measure of difference between groups. The difference is said to be significant if it is greater than what might be expected to happen by chance alone. Also called statistically significant. Clinical, having to do with the examination and treatment of patients. Fluorouracil is a drug used to treat cancers of the breast, stomach, and pancreas, and certain types of colorectal and head and neck cancers. It is also used in a cream to treat basal cell skin cancer and actinic keratosis (a skin condition that may become cancer). It is being studied in the treatment of other conditions and types of cancer. Fluorouracil stops cells from making DNA and it may kill cancer cells. It is a type of antimetabolite. Also called 5-fluorouracil, 5-FU, Adrucil, Efudex, and Fluoroplex. Colorectal cancer, cancer that develops in the colon (the longest part of the large intestine) and/or the rectum (the last several inches of the large intestine before the anus). Zidovudine is a drug that inhibits the human immunodeficiency virus (HIV) that causes AIDS. It is a type of systemic antiviral. Also called AZT.
- It is clear that, ZIDOVUDINE, 3?-AZIDO-3?DEOXYTHYMIDINE (AZT),(1) is a chemotherapic molecule commonly used as antiviral agent, alone or in combination with other drugs, in the therapy of AIDS (acquired immunodeficiency syndrome) (Acquired Immune Deficiency Syndrome) and human T-cell lymphotropic virus type I (HTLV)-I-associated adult T-cell leukemia/lymphoma.(2) Moreover, phase I and II clinical trials in gastrointestinal cancers showed that AZT contributed to regression of some tumors.(38) Regression is a decrease in the size of a tumor or in the extent of cancer in the body. Gastrointestinal, refers to the stomach and intestines. Also called GI. Antiviral is a drug used to treat infections caused by viruses. Lymphoma, cancer that begins in cells of the immune system. There are two basic categories of lymphomas. One kind is Hodgkin lymphoma, which is marked by the presence of a type of cell called the Reed-Sternberg cell. The other category is non-Hodgkin lymphomas, which includes a large, diverse group of cancers of immune system cells. Non-Hodgkin lymphomas can be further divided into cancers that have an indolent (slow-growing) course and those that have an aggressive (fast-growing) course. These subtypes behave and respond to treatment differently. Both Hodgkin and non-Hodgkin lymphomas can occur in children and adults, and prognosis and treatment depend on the stage and the type of cancer. Adult T-cell leukemia/lymphoma is an aggressive (fast-growing) type of T-cell non-Hodgkin lymphoma caused by the human T-cell leukemia virus type 1 (HTLV-1). It is marked by bone and skin lesions, high calcium levels, and enlarged lymph nodes, spleen, and liver. Also called ATLL. Therapy, treatment. Virus is in medicine, a very simple microorganism that infects cells and may cause disease. Because viruses can multiply only inside infected cells, they are not considered to be alive. Leukemia, cancer that starts in blood-forming tissue such as the bone marrow and causes large numbers of blood cells to be produced and enter the bloodstream. Molecule is the smallest particle of a substance that has all of the physical and chemical properties of that substance. Molecules are made up of one or more atoms. If they contain more than one atom, the atoms can be the same (an oxygen molecule has two oxygen atoms) or different (a water molecule has two hydrogen atoms and one oxygen atom). Biological molecules, such as proteins and DNA, can be made up of many thousands of atoms. AIDS is a disease caused by the human immunodeficiency virus (HIV). People with AIDS are at an increased risk for developing certain cancers and for infections that usually occur only in individuals with a weak immune system. Also called acquired immunodeficiency syndrome.
- One can notice, although further in vitro and in vivo evidence is needed, these results preliminarily indicate that AZT can be proposed as a potential antiparathyroid cancer agent. In vivo is in the body. The opposite of in vitro (outside the body or in the laboratory). In vitro is in the laboratory (outside the body). The opposite of in vivo (in the body).
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