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What is cancer indomethacin?
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- cancer indomethacin
Indomethacin is a drug that reduces pain, fever, swelling, and redness. It is also being used to reduce tumor-induced suppression of the immune system and to increase the effectiveness of anticancer drugs. It is a type of nonsteroidal anti-inflammatory drug (NSAID). Cancer is a term for diseases in which abnormal cells divide without control and can invade nearby tissues. Cancer cells can also spread to other parts of the body through the blood and lymph systems. There are several main types of cancer. Carcinoma is a cancer that begins in the skin or in tissues that line or cover internal organs. Sarcoma is a cancer that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Leukemia is a cancer that starts in blood-forming tissue such as the bone marrow, and causes large numbers of abnormal blood cells to be produced and enter the blood. Lymphoma and multiple myeloma are cancers that begin in the cells of the immune system. Central nervous system cancers are cancers that begin in the tissues of the brain and spinal cord. Also called malignancy.
Preview- Evidently, in Press, Corrected Proof Review NSAIDs and selectively COX-2 inhibitors as potential chemoprotective agents against cancer Nitin Kumar, , Sushma Drabu, Sambhu Charan Mondal, a Department of Pharmaceutical Technology, MIET, NH-58, Bypass Road, Baghpat Crossing, Meerut 250005, UP, India b Maharaja Surajmal Institute of Pharmacy, C-4, Janakpuri, New Delhi 110058, India. Chemoprotective is a quality of some drugs used in cancer treatment. Chemoprotective agents protect healthy tissue from the toxic effects of anticancer drugs. COX-2 is an enzyme that speeds up the formation of substances that cause inflammation and pain. It may also cause tumor cells to grow. Some tumors have high levels of COX-2 and blocking its activity may reduce tumor growth. Also called cyclooxygenase-2 and prostaglandin-endoperoxide synthase 2. Bypass is a surgical procedure in which the doctor creates a new pathway for the flow of body fluids.
- One can deduce that, scienceDirect.com - Arabian Journal of Chemistry - NSAIDs and selectively COX-2 inhibitors as potential chemoprotective agents against cancer: 1st Cancer Update
- Apparently, nSAIDs exert analgesic, antipyretic, and anti-inflammatory effects through the inhibition of COX-catalyzed biosynthesis of prostaglandins (Nakadate et al., 1982). Moreover, the ability of these NSAIDs drugs to prevent cancer is thought to be due, in part, to COX inhibition. Currently, there are two known isoforms of COX, both of which catalyze the metabolism of arachidonic acid to prostaglandin H2, a precursor to prostaglandins (Earashi et al., 1995). Analgesic is a drug that reduces pain. Analgesics include aspirin, acetaminophen, and ibuprofen. Anti-inflammatory, having to do with reducing inflammation. Metabolism is the chemical changes that take place in a cell or an organism. These changes make energy and the materials cells and organisms need to grow, reproduce, and stay healthy. Metabolism also helps get rid of toxic substances. Acid is a chemical that gives off hydrogen ions in water and forms salts by combining with certain metals. Acids have a sour taste and turn certain dyes red. Some acids made by the body, such as gastric acid, can help organs work the way they should. An example of an acid is hydrochloric acid. Acidity is measured on a scale called the pH scale. On this scale, a value of 7 is neutral, and a pH value of less than 7 to 0 shows increasing acidity. Inflammatory, having to do with inflammation (redness, swelling, pain, and a feeling of heat that helps protect tissues affected by injury or disease).
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