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Cancer Drug Rituximab Research Online
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- cancer drug rituximab research online
Rituximab is a drug used to treat certain types of B-cell non-Hodgkin lymphoma. It is also used with other drugs to treat chronic lymphocytic leukemia and rheumatoid arthritis. It is being studied in the treatment of other types of cancer and other conditions. Rituximab binds to a protein called CD20, which is found on B-cells, and may kill cancer cells. It is a type of monoclonal antibody. Also called Rituxan. Cancer is a term for diseases in which abnormal cells divide without control and can invade nearby tissues. Cancer cells can also spread to other parts of the body through the blood and lymph systems. There are several main types of cancer. Carcinoma is a cancer that begins in the skin or in tissues that line or cover internal organs. Sarcoma is a cancer that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Leukemia is a cancer that starts in blood-forming tissue such as the bone marrow, and causes large numbers of abnormal blood cells to be produced and enter the blood. Lymphoma and multiple myeloma are cancers that begin in the cells of the immune system. Central nervous system cancers are cancers that begin in the tissues of the brain and spinal cord. Also called malignancy.
Preview- Apparently, this approach further evolved when researchers realized they could use the antibody as a carrier to deliver a radioactive isotope or a toxic drug directly to the cancer cell, where it would kill the cell while sparing nearby healthy tissue. Toxic, having to do with poison or something harmful to the body. Toxic substances usually cause unwanted side effects. Isotope is a form of a chemical element in which the atoms have the same number of protons (part of the nucleus of an atom) but with a different number of neutrons (part of the nucleus of an atom). For example, carbon 12, carbon 13, and carbon 14 are isotopes of carbon. They all have six protons in the nucleus, but each has different number of neutrons. Isotopes may be used in certain medical tests and procedures. Cell is the individual unit that makes up the tissues of the body. All living things are made up of one or more cells. Antibody is a protein made by plasma cells (a type of white blood cell) in response to an antigen (a substance that causes the body to make a specific immune response). Each antibody can bind to only one specific antigen. The purpose of this binding is to help destroy the antigen. Some antibodies destroy antigens directly. Others make it easier for white blood cells to destroy the antigen. An antibody is a type of immunoglobulin. Tissue is a group or layer of cells that work together to perform a specific function. Radioactive, giving off radiation.
- It seems to be, members of the Breast Cancer Medicine Service Medicine, refers to the practices and procedures used for the prevention, treatment, or relief of symptoms of a diseases or abnormal conditions. This term may also refer to a legal drug used for the same purpose. Breast, glandular organ located on the chest. The breast is made up of connective tissue, fat, and breast tissue that contains the glands that can make milk. Also called mammary gland. Breast cancer, cancer that forms in tissues of the breast, usually the ducts (tubes that carry milk to the nipple) and lobules (glands that make milk). It occurs in both men and women, although male breast cancer is rare.
- It`s possible to observe, another tactic for using antibodies as delivery devices is attaching them to a cytotoxic agent, such as a chemotherapy drug. Gemtuzumab (Mylotarg), a drug that is used to treat acute myelogenous leukemia (AML), consists of an antibody connected to calicheamicin, a highly toxic antibiotic. Gemtuzumab, developed at the Fred Hutchinson Cancer Research Center, targets CD33, a protein found on the surface of leukemia cells. Myelogenous, having to do with, produced by, or resembling the bone marrow. Sometimes used as a synonym for myeloid; for example, acute myeloid leukemia and acute myelogenous leukemia are the same disease. AML is an aggressive (fast-growing) disease in which too many myeloblasts (immature white blood cells that are not lymphoblasts) are found in the bone marrow and blood. Also called acute myeloblastic leukemia, acute myelogenous leukemia, acute myeloid leukemia, acute nonlymphocytic leukemia, and ANLL. Protein is a molecule made up of amino acids. Proteins are needed for the body to function properly. They are the basis of body structures, such as skin and hair, and of other substances such as enzymes, cytokines, and antibodies. Acute myelogenous leukemia is an aggressive (fast-growing) disease in which too many myeloblasts (immature white blood cells that are not lymphoblasts) are found in the bone marrow and blood. Also called acute myeloblastic leukemia, acute myeloid leukemia, acute nonlymphocytic leukemia, AML, and ANLL. Chemotherapy, treatment with drugs that kill cancer cells. Mylotarg is a monoclonal antibody combined with a toxic substance that is used to treat certain types of acute myeloid leukemia in older patients and is being studied in the treatment of other types of cancer. Monoclonal antibodies are made in the laboratory and can locate and bind to substances in the body, including cancer cells. Mylotarg is a type of antibody-drug conjugate. Also called gemtuzumab and gemtuzumab ozogamicin. Acute, symptoms or signs that begin and worsen quickly; not chronic. Cytotoxic, cell-killing. Gemtuzumab is a monoclonal antibody combined with a toxic substance that is used to treat certain types of acute myeloid leukemia in older patients and is being studied in the treatment of other types of cancer. Monoclonal antibodies are made in the laboratory and can locate and bind to substances in the body, including cancer cells. Gemtuzumab is a type of antibody-drug conjugate. Also called gemtuzumab ozogamicin and Mylotarg. Leukemia, cancer that starts in blood-forming tissue such as the bone marrow and causes large numbers of blood cells to be produced and enter the bloodstream. Antibiotic is a drug used to treat infections caused by bacteria and other microorganisms.
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