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Cancer - What is toxicities
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- cancer toxicities
Cancer is a term for diseases in which abnormal cells divide without control and can invade nearby tissues. Cancer cells can also spread to other parts of the body through the blood and lymph systems. There are several main types of cancer. Carcinoma is a cancer that begins in the skin or in tissues that line or cover internal organs. Sarcoma is a cancer that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Leukemia is a cancer that starts in blood-forming tissue such as the bone marrow, and causes large numbers of abnormal blood cells to be produced and enter the blood. Lymphoma and multiple myeloma are cancers that begin in the cells of the immune system. Central nervous system cancers are cancers that begin in the tissues of the brain and spinal cord. Also called malignancy.
Preview- It would seem to be apparant that, furthermore, a subsequent study by the same group concluded that patients with high-risk prostate cancer will benefit from delivery of a BED greater than 220 Gy (10). Although LDR boost results to date are promising, with 15-year follow-up data for low- to intermediate-risk prostate cancer patients that does not show late biochemical failures (11), such benefits are offset by increased short- and long-term toxicity and reductions in quality of life after LDR treatment. HDR brachytherapy may be combined with EBRT to allow localized delivery of a higher overall dose with reported 5-year biochemical control rates of 77-93% and 5-year cause-specific survival rates of 96-98% (12-16). HDR is an amount of radiation that is greater than that given in typical radiation therapy. HDR is precisely directed at the tumor to avoid damaging healthy tissue, and may kill more cancer cells in fewer treatments. Also called high-dose radiation. Prostate is a gland in the male reproductive system. The prostate surrounds the part of the urethra (the tube that empties the bladder) just below the bladder, and produces a fluid that forms part of the semen. Toxicity is the extent to which something is poisonous or harmful. Prostate cancer, cancer that forms in tissues of the prostate (a gland in the male reproductive system found below the bladder and in front of the rectum). Prostate cancer usually occurs in older men. Cause-specific survival is the length of time from either the date of diagnosis or the start of treatment for a disease, such as cancer, to the date of death from the disease. Patients who die from causes unrelated to the disease are not counted in this measurement. In a clinical trial, measuring the cause-specific survival is one way to see how well a new treatment works. Also called CSS. Brachytherapy is a type of radiation therapy in which radioactive material sealed in needles, seeds, wires, or catheters is placed directly into or near a tumor. Also called implant radiation therapy, internal radiation therapy, and radiation brachytherapy. Localized, restricted to the site of origin, without evidence of spread. Follow-up, monitoring a person`s health over time after treatment. This includes keeping track of the health of people who participate in a clinical study or clinical trial for a period of time, both during the study and after the study ends. Quality of life is the overall enjoyment of life. Many clinical trials assess the effects of cancer and its treatment on the quality of life. These studies measure aspects of an individual`s sense of well-being and ability to carry out various activities.
- It appears that, key words: Stereotactic body radiotherapy; Prostate cancer; Toxicity; Quality of life. Radiotherapy is the use of high-energy radiation from x-rays, gamma rays, neutrons, protons, and other sources to kill cancer cells and shrink tumors. Radiation may come from a machine outside the body (external-beam radiation therapy), or it may come from radioactive material placed in the body near cancer cells (internal radiation therapy). Systemic radiotherapy uses a radioactive substance, such as a radiolabeled monoclonal antibody, that travels in the blood to tissues throughout the body. Also called irradiation and radiation therapy.
- It`s possible to deduce that, SBRT boost for prostate cancer treatment is safe and feasible with minimal acute toxicity. At 33 months late toxicity and biochemical control are promising. Acute, symptoms or signs that begin and worsen quickly; not chronic.
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