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what are chronic myeloproliferative disorders
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- chronic myeloproliferative disorders
Myeloproliferative disorder is a group of slow growing blood cancers, including chronic myelogenous leukemia, in which large numbers of abnormal red blood cells, white blood cells, or platelets grow and spread in the bone marrow and the peripheral blood. Chronic is a disease or condition that persists or progresses over a long period of time.
Preview- It would seem to be apparant that, the optimal treatment of CEL remains uncertain, partially on account of the rare incidence of this chronic myeloproliferative disorder and the variable clinical course, which can range from cases with decades of stable disease to cases with rapid progression to acute leukemia. Progression is in medicine, the course of a disease, such as cancer, as it becomes worse or spreads in the body. Acute, symptoms or signs that begin and worsen quickly; not chronic. Acute leukemia is a rapidly progressing cancer that starts in blood-forming tissue such as the bone marrow, and causes large numbers of white blood cells to be produced and enter the blood stream. Stable disease, cancer that is neither decreasing nor increasing in extent or severity. Leukemia, cancer that starts in blood-forming tissue such as the bone marrow and causes large numbers of blood cells to be produced and enter the bloodstream. Clinical, having to do with the examination and treatment of patients. Incidence is the number of new cases of a disease diagnosed each year.
- Apparently, the chronic myeloproliferative disorders consist of chronic myelogenous leukemia, polycythemia vera (p). Chronic myelogenous leukemia is a slowly progressing disease in which too many white blood cells (not lymphocytes) are made in the bone marrow. Also called chronic granulocytic leukemia, chronic myeloid leukemia, and CML. Myelogenous, having to do with, produced by, or resembling the bone marrow. Sometimes used as a synonym for myeloid; for example, acute myeloid leukemia and acute myelogenous leukemia are the same disease. Polycythemia vera is a disease in which there are too many red blood cells in the bone marrow and blood, causing the blood to thicken. The number of white blood cells and platelets may also increase. The extra blood cells may collect in the spleen and cause it to become enlarged. They may also cause bleeding problems and make clots form in blood vessels.
- One can recognize, chronic neutrophilic leukemia (CNL) is a rare chronic myeloproliferative disorder of unknown etiology, characterized by sustained peripheral blood neutrophilia (>25 109 /L) and hepatosplenomegaly. Etiology is the cause or origin of disease. Blood is a tissue with red blood cells, white blood cells, platelets, and other substances suspended in fluid called plasma. Blood takes oxygen and nutrients to the tissues, and carries away wastes. Peripheral blood, blood circulating throughout the body. Chronic neutrophilic leukemia is a disease in which too many neutrophils (a type of white blood cell) are found in the blood. The extra neutrophils may cause the spleen and liver to become enlarged. Chronic neutrophilic leukemia may stay the same for many years or it may progress quickly to acute leukemia.
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