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What is cancer endocrine therapy?
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- cancer endocrine therapy
Endocrine therapy, treatment that adds, blocks, or removes hormones. For certain conditions (such as diabetes or menopause), hormones are given to adjust low hormone levels. To slow or stop the growth of certain cancers (such as prostate and breast cancer), synthetic hormones or other drugs may be given to block the body`s natural hormones. Sometimes surgery is needed to remove the gland that makes a certain hormone. Also called hormonal therapy, hormone therapy, and hormone treatment. Endocrine, refers to tissue that makes and releases hormones that travel in the bloodstream and control the actions of other cells or organs. Some examples of endocrine tissues are the pituitary, thyroid, and adrenal glands. Therapy, treatment. Cancer is a term for diseases in which abnormal cells divide without control and can invade nearby tissues. Cancer cells can also spread to other parts of the body through the blood and lymph systems. There are several main types of cancer. Carcinoma is a cancer that begins in the skin or in tissues that line or cover internal organs. Sarcoma is a cancer that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Leukemia is a cancer that starts in blood-forming tissue such as the bone marrow, and causes large numbers of abnormal blood cells to be produced and enter the blood. Lymphoma and multiple myeloma are cancers that begin in the cells of the immune system. Central nervous system cancers are cancers that begin in the tissues of the brain and spinal cord. Also called malignancy.
Preview- You can notice, in the classical sense, endocrine therapy for breast cancer has been understood to imply disruption of the estrogen-estrogen receptor (ER) axis, either by inhibition of function of the estrogen-producing organ (ablative therapies) or by blockade or perturbation of the estrogen-ER. Estrogen is a type of hormone made by the body that helps develop and maintain female sex characteristics and the growth of long bones. Estrogens can also be made in the laboratory. They may be used as a type of birth control and to treat symptoms of menopause, menstrual disorders, osteoporosis, and other conditions. Perturbation is a disruption or disturbance. Breast, glandular organ located on the chest. The breast is made up of connective tissue, fat, and breast tissue that contains the glands that can make milk. Also called mammary gland. Breast cancer, cancer that forms in tissues of the breast, usually the ducts (tubes that carry milk to the nipple) and lobules (glands that make milk). It occurs in both men and women, although male breast cancer is rare. Receptor is a molecule inside or on the surface of a cell that binds to a specific substance and causes a specific effect in the cell. Estrogen receptor is a protein found inside the cells of the female reproductive tissue, some other types of tissue, and some cancer cells. The hormone estrogen will bind to the receptors inside the cells and may cause the cells to grow. Also called ER. Organ is a part of the body that performs a specific function. For example, the heart is an organ.
- One can recognize, as the uncontrolled activation of cellular endocrine systems is characteristic of many breast cancers, endocrine therapy should be an effective and relatively nontoxic treatment. Nontoxic, not harmful or destructive.
- You can conclude that, unfortunately, both the Premenopausal Endocrine Responsive Chemotherapy Trial (PERCHE) and Premenopausal Optimal Management IS Endocrine therapy (PROMISE) trials were closed early due to poor accrual. Hence, the most important question of whether premenopausal women with early-stage HR-positive breast cancer receiving combined endocrine therapy would benefit from chemotherapy will likely never be answered in a prospective fashion. Premenopausal, having to do with the time before menopause. Menopause ( change of life ) is the time of life when a woman`s menstrual periods stop permanently. Chemotherapy, treatment with drugs that kill cancer cells. Stage is the extent of a cancer in the body. Staging is usually based on the size of the tumor, whether lymph nodes contain cancer, and whether the cancer has spread from the original site to other parts of the body. Prospective is in medicine, a study or clinical trial in which participants are identified and then followed forward in time.
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