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Cancer - What is Mucositis incidence
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- cancer mucositis incidence
Preview- One can recognize, in two randomized, placebo (i.e., active placebo)-controlled trials conducted in head (i.e., caput)/neck (i.e., cervix, or collum) cancer patients undergoing postoperative chemoradiotherapy and in patients receiving definitive chemoradiotherapy for locally advanced head/neck cancer, intravenous palifermin administered weekly for eight weeks decreased severe oral mucositis,[,][] as graded. Postoperative, after surgery. Placebo-controlled, refers to a clinical study in which the control patients receive a placebo. Intravenous, into or within a vein (i.e., vena). Intravenous usually refers to a way of giving a drug or other substance through a needle or tube (i.e., tuba) inserted into a vein. Also called IV. Placebo is an inactive substance or treatment that looks the same as, and is given the same way as, an active drug or treatment being tested. The effects of the active drug or treatment are compared to the effects of the placebo. Oral, by or having to do with the mouth. Chemoradiotherapy, treatment that combines chemotherapy with radiation (i.e., radiatio) therapy. Also called chemoradiation. Palifermin is a form of keratinocyte growth factor (i.e., gene) (KGF) that is made in the laboratory. KGF stimulates the growth of cells that line the surface (i.e., face, or facies) of the mouth and intestinal tract (i.e., tractus). Palifermin is used to prevent and treat oral mucositis (mouth sores) caused by high-dose chemotherapy and radiation therapy in leukemia and lymphoma. Radiation therapy is the use of high-energy radiation from x-rays, gamma rays, neutrons, protons, and other sources to kill cancer cells and shrink tumors. Radiation may come from a machine outside the body (external (i.e., externus)-beam radiation therapy), or it may come from radioactive (i.e., radio-) material placed in the body near cancer cells (internal radiation therapy). Systemic radiation therapy uses a radioactive substance, such as a radiolabeled monoclonal antibody, that travels in the blood to tissues throughout the body. Also called irradiation and radiotherapy. Chemotherapy, treatment with drugs that kill cancer cells. It is also being studied in the prevention and treatment of oral mucositis and dysphagia (difficulty swallowing) in other types of cancer. Palifermin is a type of recombinant human keratinocyte growth factor. Also called Kepivance.
- It would seem to be apparant that, perspectives on cancer therapy-induced mucosal injury pathogenesis, measurement, epidemiology, and consequences for patients. Epidemiology is the study of the patterns, causes, and control of disease in groups of people.
- It seems that, mucositis incidence, severity and associated outcomes in patients with head and neck cancer receiving radiotherapy with or without chemotherapy a systematic literature review. Head and neck cancer, cancer that arises in the head or neck region (in the nasal (i.e., rhinal) cavity, sinuses, lips, mouth, salivary (i.e., sialic, or sialine) glands, throat (i.e., gullet), or larynx [voice (i.e., vox) box]).
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