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What is cancer adult progeria?
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- cancer adult progeria
Adult progeria is an inherited disorder marked by rapid aging that begins in early adolescence. Patients may be shorter than average, and have health problems such as loss and graying of hair, hardening of the arteries, thinning of the bones, diabetes, and thin, hardened skin. They also have an increased risk of cancer, especially osteosarcoma (a type of bone cancer). Adult progeria is caused by a mutation (change) in a gene involved in cell division. It is a type of autosomal recessive gene disease. Also called Werner syndrome and WS. Cancer is a term for diseases in which abnormal cells divide without control and can invade nearby tissues. Cancer cells can also spread to other parts of the body through the blood and lymph systems. There are several main types of cancer. Carcinoma is a cancer that begins in the skin or in tissues that line or cover internal organs. Sarcoma is a cancer that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Leukemia is a cancer that starts in blood-forming tissue such as the bone marrow, and causes large numbers of abnormal blood cells to be produced and enter the blood. Lymphoma and multiple myeloma are cancers that begin in the cells of the immune system. Central nervous system cancers are cancers that begin in the tissues of the brain and spinal cord. Also called malignancy.
Preview- It is often discovered that, soft-tissue sarcoma (STS) and benign meningioma have been associated with WRN, an autosomal recessive disorder characterized by premature aging, more commonly reported in Japan than elsewhere, in part because of inbreeding. In the literature we found 124 case-reports of neoplasia and WRN from Japan and 34 from outside Japan, 1939-August, 1995. Sarcoma is a cancer of the bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Neoplasia, abnormal and uncontrolled cell growth. Tissue is a group or layer of cells that work together to perform a specific function. Benign, not cancerous. Benign tumors may grow larger but do not spread to other parts of the body. Also called nonmalignant. Meningioma is a type of slow-growing tumor that forms in the meninges (thin layers of tissue that cover and protect the brain and spinal cord). Meningiomas usually occur in adults.
- One can recognize, excess of rare cancers in Werner syndrome (adult progeria). Syndrome is a set of symptoms or conditions that occur together and suggest the presence of a certain disease or an increased chance of developing the disease.
- One can presume that, multiple tumors were reported in 19 Japanese and 5 non-Japanese. In Japan, nine first-degree relatives had WRN and cancer, six of whom were concordant as to site and/or cell type. The WRN gene has been mapped to chromosome 8p. Chromosome, part of a cell that contains genetic information. Except for sperm and eggs, all human cells contain 46 chromosomes. Gene is the functional and physical unit of heredity passed from parent to offspring. Genes are pieces of DNA, and most genes contain the information for making a specific protein. Cell is the individual unit that makes up the tissues of the body. All living things are made up of one or more cells. Cell type, describes the kinds of cells found in normal or cancer tissue. The cell type is usually identified by looking under a microscope. Some examples of cell types are lymphocytes, melanocytes, and squamous cells. In cancer, it is important to know the cell type in order to diagnose the cancer, plan treatment, and determine prognosis.
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