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What is cancer 2IT-BAD monoclonal antibody 170?
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- cancer 2it-bad monoclonal antibody 170
Antibody is a protein made by plasma cells (a type of white blood cell) in response to an antigen (a substance that causes the body to make a specific immune response). Each antibody can bind to only one specific antigen. The purpose of this binding is to help destroy the antigen. Some antibodies destroy antigens directly. Others make it easier for white blood cells to destroy the antigen. An antibody is a type of immunoglobulin. 2IT-BAD monoclonal antibody 170 is a substance being studied in the treatment of cancer. It is made by linking a monoclonal antibody called 170, which binds to a protein called MUC-1, to a substance called 2IT-BAD, which binds radioactive substances. 2IT-BAD monoclonal antibody 170 may be used to detect cancer cells and kill them. It is a type of immunoconjugate. Monoclonal antibody is a type of protein made in the laboratory that can bind to substances in the body, including tumor cells. There are many kinds of monoclonal antibodies. Each monoclonal antibody is made to find one substance. Monoclonal antibodies are being used to treat some types of cancer and are being studied in the treatment of other types. They can be used alone or to carry drugs, toxins, or radioactive materials directly to a tumor. Cancer is a term for diseases in which abnormal cells divide without control and can invade nearby tissues. Cancer cells can also spread to other parts of the body through the blood and lymph systems. There are several main types of cancer. Carcinoma is a cancer that begins in the skin or in tissues that line or cover internal organs. Sarcoma is a cancer that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Leukemia is a cancer that starts in blood-forming tissue such as the bone marrow, and causes large numbers of abnormal blood cells to be produced and enter the blood. Lymphoma and multiple myeloma are cancers that begin in the cells of the immune system. Central nervous system cancers are cancers that begin in the tissues of the brain and spinal cord. Also called malignancy.
Preview- It appears to be, determine each therapeutic dose of yttrium Y 90 labeled 2. IT-BAD monoclonal antibody 170 (90. Y-2. IT-BAD-m170) based on the calculated radiation dosimetry for normal nonmarrow tissues from the pharmacokinetic study with 111. In-2. IT-BAD-m170 performed prior to each therapy course in these patients. Radiation, energy released in the form of particle or electromagnetic waves. Common sources of radiation include radon gas, cosmic rays from outer space, medical x-rays, and energy given off by a radioisotope (unstable form of a chemical element that releases radiation as it breaks down and becomes more stable). Therapeutic, having to do with treating disease and helping healing take place. Therapy, treatment. Yttrium is a metal of the rare earth group of elements. A radioactive form of yttrium may be attached to a monoclonal antibody or other molecule that can locate and bind to cancer cells and be used to diagnose or treat some types of cancer. Yttrium Y 90 is a radioactive form of the rare metal yttrium that is used in radiation therapy to treat some types of tumors. Yttrium Y 90 can be linked to a molecule, such as a monoclonal antibody, to help it locate and bind to certain substances in the body, including cancer cells. The radiation may kill the cancer cells.
- You can recognize, OUTLINE This is a dose escalation study of yttrium Y 90 labeled 2. IT-BAD monoclonal antibody 170 (90. Y-2. IT-BAD-m170).
- It`s apparent that, determine variation in indium In 111 labeled 2IT-BAD monoclonal antibody 170 (111In-2IT-BAD-m170) pharmacokinetics before and with each therapy in patients with metastatic breast cancer. Metastatic, having to do with metastasis, which is the spread of cancer from the primary site (place where it started) to other places in the body. Breast, glandular organ located on the chest. The breast is made up of connective tissue, fat, and breast tissue that contains the glands that can make milk. Also called mammary gland. Breast cancer, cancer that forms in tissues of the breast, usually the ducts (tubes that carry milk to the nipple) and lobules (glands that make milk). It occurs in both men and women, although male breast cancer is rare. Pharmacokinetics is the activity of drugs in the body over a period of time, including the processes by which drugs are absorbed, distributed in the body, localized in the tissues, and excreted.
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